r/UpliftingNews • u/AdSpecialist6598 • 1d ago
Nitrous oxide activates layer 5 prefrontal neurons via SK2 channel inhibition for antidepressant effect
https://www.nature.com/articles/s41467-025-57951-y19
u/Oldenlame 1d ago
Scientist discovers laughing gas makes people happy.
Nitrous oxide can also cause:
Low blood pressure (hypotension).
Low oxygen (hypoxia).
Fainting.
Heart attack.
Nerve damage.
Depression.
Psychosis.
Memory loss.
Muscle spasms.
Tinnitus (ringing in your ears).
Numbness, especially in your hands and feet.
Weakened immune system.
If used regularly.
"Most of the drugs I prescribe are addictive and dangerous" ~ Dr. Gregory House.
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u/TheBrockAwesome 22h ago
Lets ask Steve-O how happy it can make us. He feild tested that shit for a while.
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u/Oldenlame 20h ago
You should check out his YouTube channel. He talks about his recovery.
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u/TheBrockAwesome 19h ago
I've actually been a big fan for many years and have read his book. Its a good read.
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u/bluesmom913 1d ago
Isn’t nitrous oxide what’s in those tiny snort bottles that were prevalent in the 80’s? They certainly made you perk up for awhile
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u/TedDTedderson 1d ago
Those were probably poppers - amyl nitrate.
Here's a comparison of harm study for the two: https://journals.sagepub.com/doi/10.1177/20503245221127301
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u/reddit455 22h ago
it's the stuff the dentist gives you before they drill (laughing gas)
been a party drug for a while.
https://en.wikipedia.org/wiki/Recreational_use_of_nitrous_oxide#20th_century
Until at least 1863, low availability of equipment to produce the gas, combined with low usage of the gas for medical purposes, meant it was a relatively rare phenomenon that mainly happened among students at medical universities. When equipment became more widely available for dentistry and hospitals, most countries also restricted the legal access to buy pure nitrous oxide gas cylinders to those sectors. Even so, its use in parties continued, with gas provided by medical professionals or restaurant workers,\20])\21]) and by other legal or illegal sources.
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u/floog 14h ago
Just had laughing gas for the first time yesterday. It was ok but didn’t make me goofy at all. Made me dizzy and light headed and a little trippy (more auditory fuckery) but I was more shocked at how quickly it wore off. I was giving the pipe to breathe on while they worked on my back so I self regulated. Amazing how quickly you clear up and being bombed.
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