r/covidlonghaulers • u/perversion_aversion • Feb 04 '25

Article COVID-19 linked to increase in biomarkers for abnormal brain proteins | Imperial News | Imperial College London

https://www.imperial.ac.uk/news/260553/covid-19-linked-increase-biomarkers-abnormal-brain/
105 Upvotes

99% Upvoted

12 comments sorted by

35

u/Notmeleg Feb 04 '25

Neurodegenerative disease will be on the rise.

8

u/[deleted] Feb 05 '25

Long covid is likely a neurodegen disease. At least we have advanced to the point where research is actually looking at cerebral spinal fluid. Thats a win by itself.

14

u/Aware-Relief7155 Feb 04 '25

This absolutely terrifies me

7

u/harrowedpossum Feb 04 '25

Time for me to whip out the nattokinaise, bromelain, and curcumin it seems

5

u/Potential-Note-6464 1.5yr+ Feb 04 '25

This is why I’ll never stop masking. The cognitive effects contracting covid multiple times have to be devastating.

7

u/BrightCandle First Waver Feb 04 '25

Forgive the UK universities and research for being 4 years behind every one else, they are kind of prejudiced towards patients so they accepting that which has been obvious a lot slower than everyone else.

5

u/RipleyVanDalen Feb 04 '25

the team urges caution with the findings. They explain their observational study is unable to prove any causal links between COVID-19 and dementia. They also stress it is still unclear whether the effect is specific to SARS-CoV-2 infection, or if a similar effect could be associated with other common infections such as influenza or pneumonia

2

u/[deleted] Feb 04 '25

I wonder of this will eventually be linked via the low cerebral blood flow also found in Alzheimer’s.

1

u/WaxPoetique First Waver Feb 05 '25

Source article: https://www.nature.com/articles/s41591-024-03426-4

"SARS-CoV-2 infection was associated with biomarkers associated with β-amyloid pathology: reduced plasma Aβ42:Aβ40 ratio and, in more vulnerable participants, lower plasma Aβ42 and higher plasma pTau-181."

2

u/WaxPoetique First Waver Feb 05 '25

The increase reported in the study isn't that high:

"For an average 75-year-old participant, this model estimated an additional 8.2% increase in pTau-181, a 4.7% decrease in Aβ42 and a 2.3% decrease in the Aβ42:Aβ40 ratio in SARS-CoV-2-positive participants"