r/science Oct 08 '24

Neuroscience Brain’s waste-clearance pathways revealed for the first time. Wastes include proteins such as amyloid and tau, which have been shown to form clumps and tangles in brain images of patients with Alzheimer’s disease.

https://news.ohsu.edu/2024/10/07/brains-waste-clearance-pathways-revealed-for-the-first-time
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u/meganthem Oct 08 '24

I like the sound of this. Even if we're unlucky and it's not useful for Alzheimer's, learning about the waste-clearance system is going to be useful for treating something. There's lots of neurological disorders and problems connected to stuff getting stuck in the brain and not being cleared out properly.

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u/ConcentrateOk000 Oct 08 '24 edited Oct 09 '24

There is an amazing radiolab episode about a woman who has come up with a ‘treatment’. It uses pulsating light directly into the eyes that mimics the activity of the glymphatic system. The only downside being it only lasts hours or days. It’s insane how it isn’t talked about more, given how effective it is as removing the protein buildup.

This is it

Update: My wonderful partner is going to put the ‘sound’ through an analysis program to extract the specific wavelengths and frequencies.

We will post it on his bandcamp when finished and I’ll do another update!

Edward Stumpp

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u/[deleted] Oct 08 '24 edited Jan 21 '25

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u/[deleted] Oct 08 '24

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u/Short-Taro-5156 Oct 08 '24

I remember early on in the whole covid debacle I was posting that people who don't get a lot of sunlight should supplement with vitamin D and potentially zinc/vitamin C due to their immunomodulatory properties (also only helpful prior to infection).

Instantly dogpiled by a horde of people claiming it was pseudoscience and then banned by the mods. The worst part is I wasn't claiming it was a cure or treatment, just that it would potentially improve the clinical course of the infection in those who could potentially be deficient in those vitamins/minerals.

For reference I did attend pharmacy school, and while I don't believe that makes me the ultimate authority on the subject, I'm certainly capable of parsing the academic literature for treatment modalities that potentially show benefit.

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u/Man0fGreenGables Oct 08 '24

There is a bizarre hatred for all supplements from people on Reddit that say they are completely useless yet doctors regularly use them to treat people.

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u/sapphicsandwich Oct 08 '24 edited Oct 08 '24

Reddit insists that chiropractors have no use whatsoever. I've seen this said so many times, so when I woke up one day with a bulge in my neck and couldn't turn my head, I went to my primary care doctor. She asks why I didn't go to a chiropractor, I say I heard they were quacks. She says OK and sends me to physical therapy. I wait weeks for physical therapy, barely able to move my head, pain getting worse and worse. I get there and start doing exercises. A couple weeks of exercises and nothing changes, just the pain is getting worse. The physical therapist asks if I have tried a chiropractor. I say the same thing. I become afraid I won't be able to go to work anymore, it's seriously too bad. I finally listen to my mother and go to a chiropractor. He goes, "Oh, your vertebrae at the base of your skull is mis-aligned!" he pokes the bump and shows me a skeleton and tells me this is the joint. He pops my neck pretty gently and the relief was INSTANT. I was in and out in like 10 minutes, no mysticism, no selling of snake oil, none of the things redditors insist they always do. I can suddenly move my head. It has been a really long time and it is still good with no pain after one treatment. I still go to physical therapy to help strengthen muscles as they recommend so that it won't happen again. According to Reddit this story is completely impossible and there is no way a chiropractor could have been any help popping it back into place whatsoever, it's all just quackery, after all, every last bit of it.