r/science • u/Wagamaga • Feb 12 '25

Neuroscience The first clinical trial of its kind has found that semaglutide, distributed under the brand name Wegovy, cut the amount of alcohol people drank by about 40% and dramatically reduced people’s desire to drink

https://today.usc.edu/popular-weight-loss-diabetes-drug-shows-promise-in-reducing-cravings-for-alcohol/
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u/FeelsGoodMan2 Feb 12 '25

Oddly I am the other way around, I used to get very hungover even with small amounts of liquor which would dissuade me from casual drinking. Now, it feels like I dont get hungover nearly as often which has actually made me feel more okay with having drinks every now and then, does anyone else have that experience? It's almost like my digestion of alcohol improved or something. I also don't get nearly as affected drunk wise by the same amount of liquor as I used to.

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u/IOnceAteAFart Feb 13 '25

Hey, previous drinker, always had a bad sweet tooth, and I've always had overly bad hangovers compared to the amount I drink, even when I dont take in sugar that day (in case it's a case of too much sugar affecting alcohol digestion). But I've wondered before if it's a metabolism/digestion issue as well. New studies are showing deeper links between opioid addictions and sugar intake than ever expected, and I have to wonder if ozempic affecting digestion might somehow be directly affecting the body's tendency to addiction.

Maybe someday the effect of this drug on digestion/metabolism can isolate the effect it might have on addiction, and give a new way forward to treatment.