r/science • u/Wagamaga • Feb 12 '25

Neuroscience The first clinical trial of its kind has found that semaglutide, distributed under the brand name Wegovy, cut the amount of alcohol people drank by about 40% and dramatically reduced people’s desire to drink

https://today.usc.edu/popular-weight-loss-diabetes-drug-shows-promise-in-reducing-cravings-for-alcohol/
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u/Nancy_drewcluecrew Feb 12 '25

Same - Vyvanse had been helping a lot, but I still have issues when the medication wears off by the end of the day. It makes me want to try a GLP to see if it would help make the food/drink/addiction noise stop for a longer period of time.

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u/gaya2081 Feb 13 '25

I'm taking Saxenda which is a daily injection. I use to complain to my Dr that I wish my adhd meds effect with food could last longer than just into the early evening hours. Breakfast and lunch was never a problem, early dinner - ok.... Come 6/7pm...eat all the things and never be satisfied. Saxenda has pretty much stopped that and I've lost 40+ pounds without trying. I don't like doing daily injections because I do forget to do them some days so I'd like to switch to one of the weekly medications, but for now it's awesome and has been for almost 9 months.

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u/Pregxi Feb 13 '25

I literally just posted above that the main thing that Zepbound has done was help with the wearing down at the end of the day. Both with hunger and general tiredness too. It's kind of crazy. I don't have that thing in my head telling me to eat. And when I do eat, I seen to naturally just eat about what your body is supposed to. It feels like a magic spell to be honest.

I've been on it for 2 weeks now and I've only over eaten once and that was the day before my next dose.

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u/lineya Feb 13 '25

You can also ask your doctor about Qelbree. It's a non stimulant adhd medication that kinda builds up in your system a bit so it doesn't wear off as quickly. It has a decent level of appetite reduction on its own, I lost a bit of weight without even trying on just it, and now I take a low dose of Vyvanse on top of it and the qelbree helps mitigate the food debt feeling after it wears off.

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u/Closefromadistance Feb 14 '25

I am a lifelong sugar addict and extreme sugar binger. Mostly due to clinical depression and ptsd - I’ve also had adhd since the early 80’s.

I drank most of my life but it wasn’t as bad as my sugar/ candy addiction (bags of smarties, hot tamales, laffy taffy, entire jars of honey, entire tubs of frosting).

I started Tirzepatide last year and within moments of the first injection my sugar cravings completely stopped.

I haven’t wanted candy since! It made Vyvanse work better for me. It’s amazing and so freeing. My whole life whenever I ate something good, I couldn’t stop, but I’ve never had a major weight problem until last year.

Mainly because I exercised like crazy to burn the calories I ate, but now at age 56, it isn’t possible to out exercise my sugar addiction anymore.

I’m so thankful I found this - it will save my health!