r/science Professor | Medicine Feb 21 '25

Neuroscience The risk of developing ADHD was 3 times higher among children whose mothers used the pain-relief drug acetaminophen (paracetamol) during pregnancy. The association was stronger among daughters, with the daughters of acetaminophen-exposed mothers showing a 6.16 times higher likelihood of ADHD.

https://newsroom.uw.edu/news-releases/child-adhd-risk-linked-to-mothers-use-of-acetaminophen
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u/tortiesrock Feb 21 '25

This study cannot stablish causality, only correlation. Your baby is not going to be harmed by taking Tylenol sporadically. Probably you need a continuos exposure. A study that conflates one-time uses for pain relief to those people who take paracetamol daily for chronic pain during pregnancy is not rigurous.

There already too many things to avoid during pregnancy and the evidence is not that strong. I read a study about licorice, it found neurological defects in babies born from mothers who took daily high doses of licorice. Somehow that translates into: “licorice should be avoided during pregnancy” instead of licorice is harmful in high quantities. So do not worry.

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u/[deleted] Feb 22 '25

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u/tortiesrock Feb 22 '25

I have to disagree. Paracetamol has been reviewed before and its the only pain relief approved during pregnancy. The implications of not being able to take anything for pain relief during pregnancy are huge for the quality of life of patients. Untreated pain raises stress and causes psychological issues. To deny pain medication is akin to torture.

So no, a study that did not even take dosage and frequency into account cannot change stablished clinical practice. Specially when there is nothing else to fill the rol of paracetamol.