r/longevity • u/ResearchSlore • 3h ago
Serotonin reuptake inhibitors improve muscle stem cell function and muscle regeneration in male mice
41
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r/longevity • u/statto • Oct 25 '21
Could treating aging cause a population crisis? – Andrew Steele [OC]
255
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r/longevity • u/KitKat500 • 5d ago
Introductory Videos and Charitable Donations for Longevity Research - Apr 2025
6
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Introduction:
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Charitable Donations for Longevity Research:
Let us continue our funding efforts for our future health. Our regular donations will help to speed up Scientific Research to prevent and reverse age-related diseases. You can consider following research groups suggested by members or any other research group working on longevity.
Longevity Escape Velocity (LEV) Foundation: "Longevity Escape Velocity (LEV) Foundation exists to proactively identify and address the most challenging obstacles on the path to the widespread availability of genuinely effective treatments to prevent and reverse human age-related disease" (levf.org)
SENS Research Foundation: They fund research that uses regenerative medicine to repair the damage underlying the diseases of aging (about SENS)
LEAF/lifespan.io Various Campaigns such as Become a Lifespan Hero, SENS Mitochondrial Repair Project 2, NAD+ Mouse Project, MouseAge Project. Other options: LEAF on Amazon Smile, eBay, Humble Bundle
Dog Aging Project: "The University of Washington’s Dog Aging Project is dedicated to promoting healthy aging in people and their companion animals."
National Institute on Aging (NIA) : "NIA, one of the 27 Institutes and Centers of NIH, leads the federal government in conducting and supporting research on aging and the health and well-being of older people". (mission)
The Robert and Arlene Kogod Center on Aging at Mayo Clinic. Read more on this Reddit Comment
Vaika Foundation: Group of scientists working to prolong the lifespan and healthspan of domestic mammals. Read More on this Reddit Post
Buck Institute: Advancing the frontiers of research on aging Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.
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Thanks to following members of this subreddit who have shared their donation efforts. These are based on their public comments on this subreddit. Please share your donation efforts here. It will motivate others to participate.
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| Last Updated |
|---|
| Apr 1, 2025 |
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Summary
| Month/Year | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|
| January | $2,456.81 | $2,786.81 | $2,191.81 | $2,842.81 | $1,847.09 |
| February | $2,426.81 | $2,426.81 | $2,221.81 | $3,403.81 | $2,395.64 |
| March | $40.00 | $2,426.81 | $2,221.81 | $2,858.81 | $2,301.76 |
| April | $0.00 | $2,436.81 | $2,231.81 | $2,664.04 | $2,854.86 |
| May | $2,426.81 | $2,221.81 | $2,574.06 | $5,337.47 | |
| June | $2,426.81 | $2,221.81 | $2,554.83 | $2,723.17 | |
| July | $2,426.81 | $2,321.81 | $2,584.02 | $14,450.69 | |
| August | $2,436.81 | $2,341.81 | $2,569.58 | $6,062.38 | |
| September | $2,426.81 | $2,421.81 | $2,553.66 | $2,368.68 | |
| October | $2,626.81 | $2,421.81 | $2,341.96 | $2,735.97 | |
| November | $2,436.81 | $2,456.81 | $2,713.78 | $3,044.12 | |
| December | $2,436.81 | $2,431.81 | $2,331.81 | $2,816.86 | |
| Yearly Total: | $4,923.62 | $29,721.72 | $27,706.72 | $31,993.17 | $48,938.69 |
| Prior Years | $68,615.36 | Since 2017 | |||
| Grand Total: | $211,899.28 |
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This month donations
| Member ID | USD | Donated To | Remark | Post Link |
|---|---|---|---|---|
| {reset} | ||||
| Total | $0.00 |
r/longevity • u/user_-- • 1h ago
Regeneration leads to global tissue rejuvenation in aging sexual planarians
•
Upvotes
r/longevity • u/dan_in_ca • 2h ago
Beyond Plaques: How Methylene Blue and Ketones Address Vascular-Hypometabolism in Alzheimer's Disease
11
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r/longevity • u/jimofoz • 1d ago
Stem Cell Discovery in Human Retina May Lead to Retinal Degeneration Treatments
201
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r/longevity • u/mlhnrca • 6h ago
Dietary AGE Products Impact Insulin Resistance And Inflammation: Jaime Uribarri, M.D.
5
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r/longevity • u/Das_Haggis • 2d ago
Synaptica's neuromodulation system reduced Alzheimer’s disease progression by 44% in Phase 2 clinical trial. Company planning a pivotal Phase 3 trial, slated for later this year.
161
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r/longevity • u/chromosomalcrossover • 2d ago
The rodent aging interventions database (RAID): a data visualization tool for all studies reporting rodent lifespan extension
61
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r/longevity • u/Das_Haggis • 3d ago
Junevity's gene silencing method offers an alternative approach to cellular rejuvenation.
58
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r/longevity • u/jimofoz • 3d ago
Shingles Vaccine May Protect Against Dementia Risk
171
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r/longevity • u/Admirable_Repeat4121 • 3d ago
The Role of the Glymphatic System and Autophagy in Neurodegenerative Disease Prevention
27
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r/longevity • u/Valuable_Pop_7137 • 3d ago
Scientists Discover a New Mitigator of Senescence - Working with flies, mice, and human cells, scientists have demonstrated that a highly conserved protein can modulate cellular senescence, potentially opening a new avenue for future therapies.
62
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r/longevity • u/Valuable_Pop_7137 • 3d ago
Activation of Silent X Chromosome Might Improve Cognition - Using a mouse model, researchers from UCSF have found that the genes that become activated on the silent X chromosome might explain some sex-dependent differences in cognitive abilities during aging.
28
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r/longevity • u/Orugan972 • 4d ago
New Alzheimer’s treatment targets root causes, not just symptoms
238
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r/longevity • u/Das_Haggis • 4d ago
FibroBiologics hails brain tissue repair breakthrough – regenerative medicine company demonstrates treatment with fibroblasts can enable remyelination.
125
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r/longevity • u/lazerpants • 5d ago
It appears the Trump administration has fired Luigi Ferrucci and others from the NIA
bsky.app
323
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r/longevity • u/rperciav • 5d ago
Rhonda Patrick here. New episode with Dr. Darren Candow explores creatine’s potential to support brain longevity by enhancing bioenergetic resilience. Brain uptake is limited—higher doses (~10g/day) elevate brain creatine, slow age-related energy decline in neurons, and lower neurodamage markers.
88
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r/longevity • u/Valuable_Pop_7137 • 5d ago
Changes in Aging Adrenal Glands Disturb Hormonal Balance - In the Journal of Endocrinological Investigation, reviewers have described how aging affects the adrenal glands, which has downstream effects on the rest of the human body.
78
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r/longevity • u/Orugan972 • 8d ago
Human retinal stem-like cells with potential to repair vision loss discovered
377
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r/longevity • u/jimofoz • 8d ago
An Approach to Manufacture Large Numbers of Mitochondria for Transplantation
50
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r/longevity • u/Das_Haggis • 10d ago
Genflow begins SIRT6 gene therapy trial targeting healthspan improvements in dogs. Human programs also progressing towards the clinic.
112
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r/longevity • u/Das_Haggis • 11d ago
Turn Bio acquires advanced delivery technology for its epigenetic reprogramming therapeutics - expects skin rejuvenation clinical trials in 2026.
179
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r/longevity • u/Valuable_Pop_7137 • 11d ago
Study Suggests Alzheimer’s Prevention by Anti-Amyloid Drug - According to an open-label study from Washington University in St. Louis, the anti-amyloid drug gantenerumab reduced the risk of developing familial Alzheimer’s disease in a subgroup of participants. But the study has attracted criticism.
91
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r/longevity • u/Orugan972 • 12d ago
New Brain Metabolism Model Could Help Fight Aging, Diseases
138
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r/longevity • u/Das_Haggis • 12d ago
Unity optimistic on latest study data, despite senolytic failing to meet primary endpoint in DME trial.
35
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r/longevity • u/Sufficient_Ebb_9098 • 12d ago
Effects of intermittent senolytic therapy on bone metabolism in postmenopausal women: a phase 2 randomized controlled trial
43
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This study released last July seems to be the most recent human study of the effects of senolytics. The study looked at the effects of senolytics on bone density in aging women. Sadly there was only a minor effect on bone density.
Despite the strong preclinical + mice evidence for senolytics, it seems like most human trials haven't panned out. What do ya'll think? Do you all still see the potential in senolytics?