r/MadeMeSmile • u/seeyalaterdingdong • Jan 01 '25

Good News Science works

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59.6k Upvotes

97% Upvoted

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5.6k

u/Mooniekate Jan 01 '25

As someone who was born in the 80's, I watched HIV go from a death sentence, to an undetectable disease in my lifetime. Astonishing.

1.4k

u/StardewingMyBest Jan 01 '25

It makes me wonder what we'll be able to do in another 40 years.

62

u/TurboGranny Jan 01 '25

Various cancer vaccines are in clinical trials right now. Dude, they have a working gene therapy for sickle cell. Several labs are working on enzymes that'll EAT the A antigen off red cells effectively doubling the blood supply when it's approved. Don't even get me started on the insulin that can self regulate itself, so it disables when blood sugar is low and reenables when blood sugar is high. Wild stuff coming soon.

38

u/WalnutSnail Jan 01 '25

Huge drop in cervical cancer since the HVP vaccine. Like 50% drop.

13

u/malrexmontresor Jan 02 '25

78% now, and an add on effect of decreasing penile and anal cancers by 40-50%. Also some evidence in reducing oral cancers. It's an incredible vaccine.

9

u/WalnutSnail Jan 02 '25

Shhh...the anti safe-sex crowd will get you. Abstinence only!!!

/s...in case someone didn't get it.

3

u/Soft_Dev_92 Jan 02 '25

Love your optimism, but statistically speaking, 90% of clinical trials fail.

2

u/TurboGranny Jan 02 '25

True, with caveats. There are enough things in process right now that even 10% is still epic. :) Also, when something fails clinical trials, it isn't a dead end. You either expand the trial, make some changes to dosage, or retool it and try again. Pharma marches forward always, heh.

2

u/Pitiful_Control Jan 02 '25

And there are vaccines against AIDS currently in clinical trials. Early stages but exciting!

2

u/Sprmodelcitizen Jan 02 '25

Why are you even bringing this up when everyone else is talking about the McRib? S/