I was recently reading how it’s the strength of multiple hormones in a spot that trigger development. And as it travels across body the confluence says “hey, I can detect x% of this hormone, and y% of this hormone and z% of this hormone so I should trigger A & B genes … and presto your appendix forms.
Wouldn’t hormone disruption cause things like this?
That’s exactly right and what I’m referring to. If this was a germline mutation, x ligand would not be recognized throughout, as opposed to in one location. I’m sure it could be germline, it just looks more somatic. You’re talking about gap genes and segmentation and it incredibly cool stuff.
If this was a germline mutation, x ligand would not be recognized throughout, as opposed to in one location. I’m sure it could be germline, it just looks more somatic.
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u/ElSapio 29d ago
Probably not a germline mutation, looks like a signal pathway mutation that happened in the embryo