Giving psilocybin, the psychedelic in magic mushrooms, to rats made them more optimistic in the longer term, suggesting that the psychedelic substance could have great potential in treating a core symptom of depression in humans.

[u/mvea]

https://newatlas.com/medical/psilocybin-optimism-depression/

[u/boopbaboop]

Is it? I thought it was just that the research was poorly gathered, i.e. we don’t really know how well it’s doing because existing studies were retracted. 

[u/Klexington47 → u/boopbaboop]

No. The research is poorly gathered because of the fact that mdma has a grosse impact on social relations and power balance perception. So it skews the patient provider relationship too much to provide empirical data. As a result, it's a no go for this intended use as we won't overcome that using mdma.

[u/Intrepid-Ad4511 → u/Klexington47]

Could you ELI5 "has a grosse impact on social relations and power balance perception. So it skews the patient provider relationship too much to provide empirical data."? Please and thank you!

[u/Klexington47 → u/Intrepid-Ad4511]

Patients on mdma will try to act romantic, sexual or too friendly with their service providers. Service providers end up in inappropriate positions where conducting therapy impartially is almost impossible.

[u/OriginalUnique → u/Klexington47]

could you maybe link to some good sources on this topic? This is very interesting if true.

[u/Klexington47 → u/OriginalUnique]

Let me take a look and see if I can find what I was previously reading but in essence it's why the fda turned it down so the documents are around.

[u/Intrepid-Ad4511 → u/Klexington47]

Thank you for the reply!