r/science • u/CookMotor • Nov 02 '24

Neuroscience In a First, Scientists Found Structural, Brain-Wide Changes During Menstruation

https://www.sciencealert.com/in-a-first-scientists-found-structural-brain-wide-changes-during-menstruation
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u/popcorntrio Nov 02 '24

I hope this triggers more research and insight into treatments for PMDD, it’s completely debilitating and has only recently become more widely diagnosed, some treatment options would be life changing for a large proportion of women

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u/TourSpecialist7499 Nov 03 '24

There’s no evidence it’s related to PMDD. Yes it would make some sense, but there’s no evidence. I don’t have the link at hand, but I’ve also seen studies showing that 1/ the amount of hormone is not related to the severity of PMDD and 2/ a Spanish study showed a correlation between defense mechanisms rigidity (in other words, neurosis) and severity of PMDD.

So I’m skeptic about us finding answers to PMDD from a biochemical perspective alone.