r/science Feb 03 '25

Neuroscience Scientists discover that even mild COVID-19 can alter brain proteins linked to Alzheimer’s disease, potentially increasing dementia risk—raising urgent public health concerns.

https://www.imperial.ac.uk/news/260553/covid-19-linked-increase-biomarkers-abnormal-brain/
15.5k Upvotes

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78

u/Corleysaurus Feb 03 '25

Get vaccinated, y’all.

49

u/mb2231 Feb 03 '25

The study makes it sound like it wouldn't matter.

I've gotten the COVID vaccine each year and already have had COVID two times. It was mild but the study specifically says that mild COVID can be a contributor.

58

u/SaltZookeepergame691 Feb 03 '25

The largest “effect” (which has limitations) is explicitly in the sickest people - vaccination should absolutely help. It isn’t binary.

36

u/Corleysaurus Feb 03 '25

Yes, but, being vaccinated can largely prevent severe COVID cases/hospitalization, which the article indicates is connected to a worsening of this issue.

2

u/Think_Discipline_90 Feb 03 '25 edited Feb 03 '25

What kind of logic tells you mild vs severe carries the same risk?

5

u/aguyinphuket Feb 03 '25

Perhaps not the same risks, but there is not necessarily a direct correlation between the severity of pulmonary symptoms caused by COVID infection and the severity of the damage to proteins in the brain such an infection can cause.

-1

u/Think_Discipline_90 Feb 03 '25

Anything is possible, yes.

1

u/fadingsignal Feb 04 '25

It's not logic, studies point to this. People are still too focused on the acute phase of COVID (rightly so considering how it behaved in early 2020.) But it gets everywhere through the body and causes myriad downstream issues we still don't understand.

Here's one about neurological effects and how severity or vaccination doesn't affect outcome:

https://news.nm.org/new-research-finds-covid-19-vaccination-prior-to-infection-does-not-affect-the-neurological-symptoms-of-long-covid

Here's one on how long-COVID appears to stem more from mild cases than acute ones:

https://www.govexec.com/management/2023/01/long-covid-stemmed-mild-cases-covid-19-most-people-according-new-multicountry-study/381491/

1

u/[deleted] Feb 04 '25

Scientific method. You are making an assumption

1

u/Think_Discipline_90 Feb 04 '25

I am, and so is he. Haven't tested either hypothesis, so it's best to assume vaccines still help.

1

u/[deleted] Feb 04 '25

No. It's best not to assume and get proper studies done.

1

u/Think_Discipline_90 Feb 04 '25

Okay. Then stop taking vaccines until we have figured out the universe.

1

u/[deleted] Feb 04 '25

[deleted]

1

u/Think_Discipline_90 Feb 04 '25

You know you're just being annoying and pedantic now. Probably mid college age?

1

u/[deleted] Feb 04 '25

[deleted]

2

u/Think_Discipline_90 Feb 04 '25

Okay I will thanks bye

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u/fadingsignal Feb 04 '25

There was also some new information that vaccinated or not, severe or mild, didn't matter when it came to the neurological outcomes from COVID infections. Vaccines cut death/acute severity way down, but verdict is out on all of the other myriad damage COVID is still doing through the body. We don't know enough about COVID to let it rip like we did.

https://news.nm.org/new-research-finds-covid-19-vaccination-prior-to-infection-does-not-affect-the-neurological-symptoms-of-long-covid/

According to new research published in Brain Communications, Northwestern Medicine researchers found that vaccination prior to COVID-19 infection did not significantly affect neurological symptoms in long COVID patients, both in patients who had a severe infection that required hospitalization and those with a mild infection who did not require hospitalization. Common neurological symptoms of long COVID include brain fog, numbness and tingling, headache, dizziness, problems with smell and taste and intense fatigue.