r/science • u/Potential_Being_7226 PhD | Psychology | Neuroscience • 14d ago

Neuroscience Boosting brain’s waste removal system improves memory in old mice | Researchers found that rejuvenating the lymphatic vessels in the brain enhanced recognition memory and restored synaptic function through an interleukin-6 (IL-6) pathway.

https://medicine.washu.edu/news/boosting-brains-waste-removal-system-improves-memory-in-old-mice/
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u/IOnlyLiftSammiches 14d ago edited 14d ago

Could be the difference between those that get a "runner's high" from exercise vs those that don't. If I'm going to have to stay awake for longer than normal (adjusting for swing shifts), I plan for my exercise to take place before the last 6-8 hours of that because it gives me such a mental and physical energy boost.

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u/deanusMachinus 14d ago

Doesn’t everyone get a runner’s high if you run long enough? It just takes 20+ mins of running and most people can’t do that.

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u/ClutchCobra 14d ago

I honestly think some people don't, maybe it's a genetic thing, maybe it's a learned thing, but some are adamant that exercise them discomfort.

And it would really suck for that to be your experience. I couldn't imagine exercising without that rush on endorphins and confidence. It's gotten to the point where my energy levels paradoxically tank on the days I don't exercise. If I'm working a long shift I feel twice as alert throughout the day when I've exercised before

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u/MyFiteSong 14d ago edited 14d ago

There's a high correlation between not receiving the endorphin rush from running and having ADHD. I never believed that high was real until I tried exercising on stimulants.