Boosting brain’s waste removal system improves memory in old mice | Researchers found that rejuvenating the lymphatic vessels in the brain enhanced recognition memory and restored synaptic function through an interleukin-6 (IL-6) pathway.

[u/Potential_Being_7226]

https://medicine.washu.edu/news/boosting-brains-waste-removal-system-improves-memory-in-old-mice/

[u/chessmasterjj]

How do we clean out our brain of waste? 

Edit: Just says they boosted the lymphatic system of the mice, doesn't say how. If you give "strengthen lymphatic system" a Goog you get physical exercise, hydration and healthy diet. 

[u/TsuDhoNimh2 → u/chessmasterjj]

Here is a link to the study for you. https://www.cell.com/cell/fulltext/S0092-8674(25)00210-700210-7)

It goes into detail how they tested what impeded meningeal lymphatic drainage did.

And what they did: injected VEGF-C into the mouse brains.

Intracisternal injection of AAV1-CMV-mVEGF-C in aged mice has been shown to enhance the coverage and function of meningeal lymphatics, accompanied by restoration of cognitive deficits.⁹00210-7#bib9)^,3500210-7#bib35) We delivered AAV1-CMV-mVEGF-C (AAV1-CMV-EGFP was used as a control) and assessed synaptic and behavioral phenotypes 4 weeks later (Figure 500210-7#fig5)C).

https://en.wikipedia.org/wiki/Vascular_endothelial_growth_factor_C