r/Microbiome 1h ago

What’s your ideal fiber intake?

Upvotes

I’ve been having trouble putting on weight , mostly because of my fiber intake - 40g a day.. so I’m gonna try lowering to 20-25 with just more fermented foods ie kimchi instead of broccoli


r/Microbiome 10h ago

Human growth hormone (somatropin) ???

0 Upvotes

After a year and a half of treating disbiosis with no favorable results I have decided to do a human growth hormone cycle that will last about 4-5 months. There are endless reasons to why I'm enthusiastic about this non-conventional treatment. If you have any insights on this matter; somatropin v gut microbiome please share. Thanks


r/Microbiome 1d ago

Fulvic acid side effect

0 Upvotes

Can anyone relate or is it all in my head. I took fulvic acid a few months to help with digestive health but I think it affected my vision. The world around me seems cloudy and not real. When I google the symptoms derealization comes up but I’ve never had an issue with anxiety or depression. The world looks different now, feels like I’m in a dream. So far I haven’t spoken to anyone who had similar side effects. My optometrist said my vision was still perfect


r/Microbiome 6h ago

Somatropin HGH - gut studies

0 Upvotes

So I got banned for posting a question about this subject (title) by a mod that said that I had no right to post about something that is completely experimental, dangerous and something about blackmarket drugs ( I did not mention anything on this matter). I received 3 total replies before being banned and here is the reply for those who are more interested; Yes there is science to back this up. Here are some articles to prove it.

  1. https://www.nature.com/articles/pr199587?utm_source=chatgpt.com

  2. https://pmc.ncbi.nlm.nih.gov/articles/PMC1027008/?utm_source=chatgpt.com

  3. https://www.scielo.br/j/bjmbr/a/gwPSm3TPWBfTB4j8YdDThkH/?utm_source=chatgpt.com

  4. https://pubmed.ncbi.nlm.nih.gov/16083754/?utm_source=chatgpt.com

Study description:

  1. Small Intestine:

Intestinal Ion Transport: A study published in Pediatric Research examined the acute administration of hGH on rat ileum. The results indicated that hGH rapidly increased the absorption rates of water, sodium, chloride, and potassium. In vitro experiments showed that hGH decreased transepithelial potential difference and short-circuit current, suggesting an inhibition of basal active chloride secretion. These findings suggest that hGH has a direct antisecretory effect on the intestine, enhancing its absorptive function.

Mucosal Growth and Proliferation: Research published in Gut explored the trophic actions of hGH, insulin-like growth factor-I (IGF-I), and insulin on human duodenal mucosa cultured in vitro. The study found that all three hormones significantly increased crypt epithelial cell proliferation, with IGF-I being the most potent. This indicates that hGH and its mediators play a role in regulating cell proliferation in the human small intestine.

Intestinal Barrier Function in Sepsis: A study in the Brazilian Journal of Medical and Biological Research investigated the effects of recombinant human growth hormone (rhGH) on the intestinal mucosa barrier in septic rats. The results demonstrated that rhGH attenuated intestinal mucosal injuries and bacterial translocation. Additionally, rhGH influenced the expression of proteins related to apoptosis, suggesting a protective role in maintaining intestinal integrity during sepsis.

Post-Trauma Intestinal Homeostasis: Research in PubMed assessed the impact of growth hormone on gut mucosal homeostasis after severe trauma. The study found that while hGH did not significantly affect small bowel epithelial cell apoptosis or proliferation, it improved villous morphology, indicating a role in maintaining intestinal structure post-injury.

  1. Pancreas:

While the provided studies primarily focus on the intestines, research indicates that hGH can influence pancreatic function. hGH has been shown to induce insulin resistance in peripheral tissues, prompting the pancreas to increase insulin secretion to maintain glucose homeostasis. Over time, this increased demand may stress pancreatic β-cells.

  1. Colon:

Specific studies directly examining the effects of hGH on the colon are limited. However, the general trophic effects of hGH on intestinal mucosa suggest potential influences on colonic tissues, warranting further investigation.


r/Microbiome 13h ago

Colostrum?

1 Upvotes

Hi! I started using colostrum from a well know brand a few months ago and while I haven’t had any negative side effects, I haven’t really noticed a huge difference. Anyone have experience using colostrum? What should I be looking out for?


r/Microbiome 3h ago

Antinutrients free Oat alternative

0 Upvotes

Hello everyone,

Does anyone know of an antinutrient-free oat alternative?

Due to intestinal problems and food allergies,

I'm currently switching my diet to only natural foods.

I used to eat oatmeal with yogurt, wild blueberries, and honey, but the antinutrients in oatmeal are causing me major problems (gluten isn't a problem for me).

I'm happy to hear any suggestions.


r/Microbiome 10h ago

Scientists reveal new toxin that damages the gut

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10 Upvotes

r/Microbiome 10h ago

Why we should all try to eat like people in rural Papua New Guinea – new study

11 Upvotes

r/Microbiome 10h ago

This stuff has changed my life!

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186 Upvotes

r/Microbiome 12m ago

Help

Upvotes

Hi. I’ve been lurking on this sub for a while. I was diagnosed with gerd a few years ago, last year had my gallbladder out. Im struggling with reflux and right rib pain. I feel my microbiome is messed up, I’m looking for helpful tips to improve my gut. Doctors are useless, all they do is tell you to take a ppi and that does help.


r/Microbiome 31m ago

Human gut microbiota

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Upvotes

r/Microbiome 1h ago

Advice Wanted Probiotics making my stomach feel worse

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Upvotes

I have been taking this pill with probiotics (you look well day pill) for about 2 weeks, my stomach settled about 4 days in but it feels like it is getting worse now - Burning acid reflux type pain in my stomach. Should i continue and push through in the hopes it will improve?


r/Microbiome 4h ago

Advice Wanted White specks in stool

1 Upvotes

12 days ago i had food poisoning from raw milk (i believe i got campylobacter if i remember correctly what the doctor said)

i had fever first 2 days then bloody diarrhea for a few days once the fever passed

my stool color turned normal but i had stomach cramps while pooping up to like day 9

doctor only prescribed me with a stomach relaxer

the only symptoms i have left now is white specks in my stool and an ithcy anus from time to time

im paranoid this could be the start of an autoimmune / chronic disease and that my symptoms might show up again since reading that food poisoning can be the start of life long digestive diseases


r/Microbiome 6h ago

Low stomach acid ???

2 Upvotes

I suddenly developed constipation 5 months after contracting ghsv1 and after a 2 week alchohol binge and it hasn’t gotten better since. I feel like my food just sits in my stomach , I don’t have a urge to poop but when I do poop it’s soft loose stools . I burp all day and have really smelly gas . When I do an enema there’s barely anything that comes out , laxatives rarely work. I noticed there’s undigested food in my stool and sometimes my stool is green . I got a colonoscopy and my colon is fine they say. I’ve been doing research I know about sibo etc, which I’m sure could be a factor. All the doctors wanna do I put me on miralax and linzess which doesn’t work .


r/Microbiome 7h ago

Advice Wanted Weird Question on Amoxicillin

1 Upvotes

I’ve started a one week course of amoxicillin and am 4 days in. 500mg three times a day. It just started today but I get whiffs of smoke/campfire that no else seems to smell. Has anyone else experienced random smells when on amoxicillin. Of course google says brain tumor so that didn’t help.


r/Microbiome 8h ago

Scientific Article Discussion Microecology in vitro model replicates the human skin microbiome interactions (2025)

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nature.com
2 Upvotes

r/Microbiome 8h ago

Scientific Article Discussion Conversation between skin microbiota and the host: from early life to adulthood (2025)

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nature.com
6 Upvotes

r/Microbiome 8h ago

Scientific Article Discussion Modulation of Host Immunity by Microbiome-Derived Indole-3-Propionic Acid and Other Bacterial Metabolites (2025)

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1 Upvotes

r/Microbiome 8h ago

Scientific Article Discussion Life-long microbiome rejuvenation improves intestinal barrier function and inflammaging in mice (2025)

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3 Upvotes

r/Microbiome 11h ago

Scientific Article Discussion Gut Microbiome-Produced Bile Acid Metabolite Lengthens Circadian Period in Host Intestinal Cells (2025)

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biorxiv.org
5 Upvotes